onlyone™ Heart is a once-daily supplement containing 8 clinically informed foundational nutrients specifically formulated for men and women whose bodies may be managing the nutritional gaps that come with aging and statin therapy.

OnlyOne™ Heart is formulated with bioactive nutrient forms selected for stability, optimal bioavailability, and physiological relevance. Each ingredient is included at levels informed by human clinical research and established safety data. The formula is thoughtfully developed for men who use statin medications, providing targeted nutritional support for long-term cardiovascular wellness with integrity, regulatory compliance, and scientific rigor at the forefront. No pill organizer. No second-guessing. Just a formula that consolidates the key nutritional gaps that research shows come with statin use and aging into a once daily dose. Explore the full formula on our Ingredients page.

onlyone™ Heart was designed specifically for adults on statin therapy or who are concerned about their cardiovascular health who want to fill the nutritional gaps that research shows come with long-term statin use or age. The ingredients are among the most discussed an studied in the clinical literature around heart health.

If you’re managing your cardiovascular health with a statin and looking for a single, well-formulated daily supplement to support your cardiovascular health, this is for you.

Not on statins?

The formula also addresses common, foundational nutrient gaps in adults over 40, generally, especially those concerned about their cardiovascular needs.

onlyone™ Heart was built by a statin user, primarily for statin users. Statins work as intended to reduce LDL and also have documented effects on CoQ10 levels which affect cellular energy. But statins save lives, regardless of any real or perceived issues patients have with them, which should always be discussed with your doctor. We are pro-cardiologist, and pro-medical establishment, and have built and positioned onlyone™ Heart to work alongside your doctor-prescribed medication, not against it, or in place of it.

No. onlyone™ Heart is a dietary supplement, not a medication. It is not designed to replace any prescribed medication. Always continue taking your prescribed medications as directed by your doctor. onlyone™ Heart supports your overall nutritional health alongside your treatment plan, not instead of it. It is the perfect complement to your statin.

Yes, and we’d encourage it. We’re pro-doctor, not a substitute for one. If you have specific health concerns, are on multiple medications, or are unsure whether any ingredient is appropriate for you, run it by your cardiologist first. Note: if you are on Warfarin or another blood thinner, you should specifically flag the Vitamin K2 content with your doctor before starting.

Each dose contains the highest quality ingredients and also the appropriate dosing we believe to be functionally beneficial for your body. That means that a lot of stuff had to be packed in. There’s no room for fillers and cheap synthetic forms of important nutrients. This is your heart we are talking about. The dosage has been reviewed by pharmacologists, biochemists, nutritionists and cardiologists. Some all-in-one dailies have miniscule amounts of what you need just so they can claim it on the label. Not here. 

In some cases, your doctor or cardiologist may suggest higher doses

We are extremely concerned about our ecological impact. While many plastics can be recycled, they often end up in the dump. This can be especially true of vitamin and supplement bottles. We have chosen a packaging company called ePac, whose values align with ours. The pouch your product is shipped in is safe for your capsules. The package should be resealed properly for protection and freshness when not in use, and your capsules should be consumed as directed to ensure the integrity of the capsule.

Yes! The first conversations I had about the product I wanted to make to help me, and others in my situation, were with my cardiologist. We have two cardiologists in advisory capacity, and we also have a cardiac dietician on board too. We also have consultants in vitamin chemistry, pharmacy, and compliance who have been involved along the way.

• Dr Danny Eapen M.D. - Dr. Eapen is a board-certified cardiologist based in Houston, TX. He completed his medical degree at the University of Miami School of Medicine before completing fellowships in both cardiovascular biology research and clinical cardiology at Emory University School of Medicine and the Emory Clinical Cardiovascular Research Institute.
• Dr Natalia Tovar - Dr. Tovar is an interventional cardiologist currently practicing at Clínica Rotger in Palma, Spain. She trained in cardiology at Hospital Universitario 12 de Octubre in Madrid and completed her interventional fellowship at Erasmus MC in Rotterdam — one of Europe's leading cardiovascular centers.
• Julia Zumpano - Julia is a Registered Dietitian and Nutrition Media Liaison at the world renowned Cleveland Clinic, where she has specialized in disease prevention and management for over 20 years — with a particular focus on heart disease, diabetes, hypertension, and metabolic syndrome. She also contracts with FWDfuel Sports Nutrition. The Cleveland Clinic is not affiliated with onlyone™ Heart.

We currently only ship within the United States. As this is a health supplement, other countries may have differing statutes governing ingredients and shipping. New markets will open in time.

Standard delivery is 3-5 business days. Currently we are using USPS.

Standard shipping is free on all orders.

Yes. Once your order ships you will receive a confirmation email with a tracking number.

If your order arrives damaged or is lost in transit, please contact us at stephen@onlyoneheart.com within 14 days and we will make it right.

Take 2 capsules once daily, ideally in the morning with food and water. That’s it. No complicated routine. Morning with breakfast works well because several of the nutrients, including CoQ10 and D3, are fat-soluble and are absorbed better with a meal.

The formula was designed with statin users in mind, but the nutritional gaps it addresses, declining CoQ10, lower magnesium absorption, reduced B12 and D3 levels with age, are common in adults over 40 generally. If you’re over 40 and looking for a clean, well-formulated daily cardiovascular supplement, it may still be right for you.

Yes! The capsules are Vegan/Vegetarian. And made with Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. And are not made with wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts, or sesame, however, they are produced in a facility that also produces products with these ingredients.

Yes, onlyone™ Heart is gluten-free. Please refer to the full label for allergen information.

We offer a 60-day satisfaction guarantee. If you’re not satisfied for any reason within 60 days of purchase, contact us here and we will process a full refund. No questions asked. We believe in the formula. If you feel it’s not working for you though, we’d rather refund you than keep your money.

For more details, please see Refund Policy here.

Statins work by inhibiting the mevalonate pathway, which is responsible for producing both cholesterol and CoQ10. Multiple studies confirm statin therapy reduces circulating CoQ10 levels by 16,54%. CoQ10 plays an essential role in mitochondrial energy production*. We use ubiquinol, the active, reduced form, because conversion efficiency from the cheaper ubiquinone form declines significantly with age.

Ubiquinol is the active, reduced form of CoQ10. It’s what your cells actually use. Ubiquinone requires conversion before the body can use it, a step that becomes less efficient as you age. We use ubiquinol because it’s the better choice for this demographic, even though it costs us more to source.

Magnesium glycinate has one of the highest bioavailability ratings among magnesium forms and is significantly more absorbed than magnesium oxide, the cheapest and most common form, and gentler on the digestive system than magnesium citrate. If you’ve had digestive issues with magnesium supplements before, the form might be why. Glycinate is recognized for digestive tolerance and high bioavailability*.

Vitamin K2 plays a role in activating proteins that help guide calcium to where it belongs in the body, including bones and teeth, while supporting normal vascular function.* Because statin therapy works by influencing the body’s cholesterol production pathway, it may also affect the production of certain downstream compounds involved in cellular processes. Rather than relying solely on internal conversion, we include vitamin K2 (MK-7) directly in the formula to provide consistent nutritional support.* Important: Vitamin K2 can interact with anticoagulant medications, including Warfarin. If you are on a blood thinner of any kind, please consult your doctor before taking onlyone™ Heart.

No. Every ingredient and every dose is fully disclosed on the label. No hidden amounts, no proprietary blends that allow manufacturers to use trace amounts and still list something. You have the right to know exactly what you’re putting in your body. We think transparency should be the standard, not the exception.

onlyone Heart contains a targeted blend of nutritional support that clinical evidence shows can be deficient in people focusing on their cardiovascular health. This can happen due to age, medication, or in some cases diet. For example some heart healthy diets, while they can help manage cholesterol, may also mean your body does not receive optimal levels of B vitamins which have been linked to mental clarity or focus or Zinc which has been linked to testosterone support. The aim of onlyone heart is to help you get your body's foundational needs met in the simplest way possible and is designed specifically for those concerned with heart health or those on statins.

And since nutrients like magnesium have been shown to be involved in over 300 enzymatic reactions in the body, you may find some it provides support or promotes wellness in other areas of your overall health like better sleep.

onlyone™ Heart is a dietary supplement, not a drug, but every ingredient supports nutritional functions related to heart health.

• CoQ10 supports cellular energy production* which can be associated with muscle fatigue
• Magnesium Glycinate supports healthy muscle function* and has been linked to better sleep quality and muscle recovery* as well as promoting healthy inflammation response*.
• B vitamins support homocysteine metabolism* and mental focus* , and mood regulation*
• D3 and K2 support cardiovascular and bone health*. D3 is also linked o immune support and mood regulation.
• Zinc supports antioxidant and immune function,* as well as a health inflammatory response.

The goal is to address the nutritional gaps, not to promise a transformation.

Supplements aren’t drugs. They support normal body functions and build up optimal nutrient levels over time rather than delivering an immediate effect. Most nutritional experts recommend giving any supplement regimen at least 60-90 days before assessing or drawing bloodwork comparisons. We offer a 60-day satisfaction guarantee for exactly this reason: we want you to have enough time to actually evaluate it fairly.

We also recommend asking your doctor for heart related nutrient panel if your insurance will cover it. That way you can track improvements. There are also companies like Function Health who offer many tests throughout labs across the US and who accept HSA and FSA funds as well. www.functionhealth.com (we are not affiliated with Function Health but we believe in their mission).

onlyone™ Heart is designed to complement, not interfere with, your statin therapy. That said, if you have specific concerns about any individual ingredient interacting with your medications, always run it by your cardiologist. We are pro-doctor, not a substitute for one. The one specific note: if you are on Warfarin or another anticoagulant, consult your doctor about the Vitamin K2 content before starting.

We can’t make that claim, and we won’t. What we can say is that CoQ10 depletion through the mevalonate pathway is a documented biochemical consequence of statin therapy. CoQ10 is important for cellular energy production* which could present as muscle fatigue if comprised. But deficient levels of magnesium could also be associated with muscle pain and slower muscle recovery. These two may be conflated. If you believe you are experiencing muscle symptoms on statins, speak to your cardiologist. Don’t self-manage it. You rcardiologist or doctor may be able to adjust your medications. onlyone™ Heart has been designed with you in mind to help support foundational nutrient requirements but are not a replacement for doctor prescribed statin therapy.

Yes. We show our work. Every ingredient in onlyone™ Heart has published, peer-reviewed research behind our decision to include it. Visit our Ingredients page for evidence rationale. We believe in transparency: if the science isn’t there, the ingredient isn’t in the formula.

Due to regulatory constraints as a supplement, we have not put every study on the Website. But if you are a clinician and would like to request an our clinical study dossier please use our contact form to request it, and we will happily send it to you.