onlyone™ Heart

These nutrients don't work in isolation. CoQ10 supports cellular energy production, magnesium glycinate plays a role in healthy muscle function, and the B vitamins, folate, and K2 all contribute to processes that matter for cardiovascular health. The combination is the point.

- Julia Zumpano, Registered Dietitian, Cleveland Clinic

Daily 8-in-1 cardiovascular support for adults using cholesterol lowering medications like statins. Two capsules. Once daily. To combat nutrient depletion. 

A system designed to work together:

Cellular Energy - Supports energy production at the mitochondrial level* 

Heart Muscle - Supports healthy muscle performance and comfort*

Arterial and Antioxidant support - Supports healthy calcium metabolism and the body's normal inflammatory response*

Homocysteine metabolism - Supports the methylation pathway for homocysteine clearing* 

Blood Pressure - Supports healthy blood pressure levels already within the normal range.*

Learn more about its key benefits and how it can become part of your heart health journey.

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Why Choose onlyone™ Heart
Third-Party TestedGMP-Certified QualityNo Artificial Fillers

onlyone™ Heart is a precision-formulated daily supplement built to support the nutritional needs of adults focused on cardiovascular health. Eight nutrients in one pouch: ubiquinol CoQ10, magnesium glycinate, methylated B6, B9 and B12, zinc, and vitamins D3 and K2.

Every ingredient is included in a form chosen for bioavailability and metabolic relevance, so your body can actually absorb and use it. No filler, no kitchen sink. Just a foundational formula designed to complement your everyday heart health routine.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Adults using cholesterol-lowering medications like statins who want a targeted approach to daily cardiac nutritional support. It's designed to work alongside the care your doctor prescribes, not to replace it.*

It may be particularly relevant if you're looking to support healthy energy levels, a healthy inflammatory response, muscle performance, and long-term vitality as you age.*

"Most of my patients on cardiac medications are already managing a lot. Consolidating the key nutrients into one daily routine rather than five or six separate bottles is a meaningful step toward consistency. And consistency is what makes the difference." Julia Zumpano, Cardiac Dietitian, The Cleveland Clinic


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

onlyone™ Heart provides targeted nutritional support across several important physiological systems:

Cellular Energy Support
Helps support the body’s natural energy production processes and cellular energy metabolism.*

Inflammation and Arterial Support
Supports inflammation response and healthy calcium routing*

Muscle Function and Rhythm Support
Helps support healthy heart muscle performance and comfort.*

Cardiovascular Wellness Support
Supports cardiovascular system function and healthy blood pressure levels already within the normal range.*

Methylation Support
Active B vitamins help support healthy homocysteine metabolism.*

Healthy Aging Support
Helps support sustained vitality and long-term wellness.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Each serving includes ingredients most talked about in the clinical literature around heart health:

  • Ubiquinol CoQ10, 150 mg
  • Magnesium BiGlycinate, 125 mg elemental
  • Zinc Bisglycinate Chelate, 10 mg
  • Vitamin B6 (Pyridoxal-5-Phosphate), 2 mg
  • Vitamin B12 (Methylcobalamin), 400 mcg
  • Folate as Quatrefolic® (5-Methyltetrahydrofolate), 500 mcg DFE
  • Vitamin D3 (as Cholecalciferol) , 2000 IU
  • Vitamin K2 (as MK-7 Menaquinone-7), 100 mcg

Other ingredients:

Vegetable capsule, plant-derived excipients.

Adults: Take 2 capsules daily, best taken with food for maximum absorption, or as directed by a healthcare professional.

Consistent daily use is recommended. Individual responses may vary.

If you are taking prescription medications or blood thinners, consult your healthcare provider before starting any new supplement.

Made right. No compromises.

Step 1
Take 2 capsules once daily with food and water.

onlyone™ Heart was designed to fit into a real daily routine, with a once-daily serving that keeps things simple from the start.

Step 2
Pair it with a habit you already have.

Whether that’s breakfast, your morning supplements, or your first glass of water, anchoring it to an existing habit makes daily use feel more natural and sustainable over time.

Step 3
Keep the routine simple and stick with it.

With one formula and one daily habit, there’s less to organize, less to second-guess, and less friction standing between you and consistency.

How onlyone™ Heart supports daily heart health.

A research-led blend of eight nutrients designed to support key aspects of cardiovascular health.*

Supports Cellular Energy

Helps support mitochondrial energy production involved in daily heart function.*

Defense & Resilience

Supports a healthy inflammatory response and antioxidant defense*

Supports Vascular Tone

Supports muscle relaxation and electrolyte balance involved in cardiac function.*

Supports Healthy Homocysteine Metabolism

Supports normal methylation processes and helps maintain homocysteine levels already within the normal range.

Supports Vascular Function

Supports calcium routing and vascular health.*

Hi, I’m Stephen.

We started onlyone™ Heart because after my heart attack, I did everything I was supposed to do. I cleaned up my diet. I took my statin every day (still do). I stayed active. But my energy wasn’t steady. Workouts took longer to recover from. I felt more tired than I expected for someone trying to do everything right.

And I wanted to be here, fully here, for my wife, my kids, my family.

Everything in one place, for a reason

Eight nutrients. More than one job each.

Beyond the five core heart benefits of onlyone™ Heart, these same nutrients in our formula have been studied for their role in supporting: 

  • Calm and rest. Magnesium glycinate supports muscle relaxation and normal nervous system function and healthy sleep cycles, helping the body handle everyday stress. It's the benefit people tend to notice at the end of the day.*
  • Mental sharpness. B12, folate and B6 support normal cognitive function and healthy nerve signaling.*
  • Bones. D3, K2 and magnesium work as a set: D3 helps you absorb calcium, K2 helps direct it toward bone, magnesium helps put it to use.*
  • Everyday immune defense. Zinc and vitamin D3 are two of the most-studied nutrients for normal immune function.*
  • Blood and oxygen. B12 and folate support normal red blood cell formation, which is how oxygen reaches everything else.*
  • Inflammatory balance. Zinc supports a healthy inflammatory response.*

No proprietary blends. Every ingredient and dose is printed on the label, in bioavailable forms, with no artificial fillers.

Made in the USA in an FDA-registered, GMP-certified facility. Vegan. Cruelty-free.

Learn More

"My patients frequently ask about nutritional support when managing cardiovascular health. A formulation that combines commonly discussed ingredients in the scientific literature such as CoQ10, magnesium, and B vitamins into a single product simplifies supplementation and may ease pill burden that many of our patients deal with."

- Dr. Danny Eapen, Board Certified - Cardiologist and member of the onlyone™ Heart Scientific Advisory Board

No B.S. Essentials

onlyone™ Heart targets nutrient gaps caused by cholesterol-lowering medications and natural aging. With key nutrients like CoQ10, magnesium, zinc, and B vitamins, it supports mitochondrial function, vascular health, and overall vitality*.

CoQ10 (Ubiquinol) 150mg

Statins can reduce the body’s natural CoQ10 production by affecting the same pathway used to make it. That’s why onlyone™ Heart uses ubiquinol, the active form the body can use right away. CoQ10 supports antioxidant defenses and cellular energy production involved in heart muscle function.*

Magnesium Glycinate 125mg

Magnesium levels can decline with age, and many adults over 40 may not be getting enough. onlyone™ Heart uses glycinate, a well-absorbed and well-tolerated form chosen for its role in muscle relaxation, electrolyte balance, and cardiovascular function.*

Zinc 10mg

Zinc is used as a cofactor for antioxidant enzymes. Anti-inflammatory activity increasingly is recognized as central to cardiovascular risk reduction beyond cholesterol management. Dietary intake commonly declines with age, particularly among adults following heart-healthy diets*

Vitamin B6 (P-5-P) 2mg, B12 (Methylcobalamin) 400mcg, Folate (5-MTHF) 500mcg

These three B-pathway nutrients work together to support methylation and healthy homocysteine metabolism: a key, often-overlooked factor in cardiovascular health. onlyone™ Heart uses active, methylated bioavailable forms selected for effective daily support.*

Vitamin D3 2000 IU

Vitamin D3 supports calcium regulation, healthy immune function, and normal muscle function. Paired with K2, it supports proper calcium utilization — helping maintain healthy arteries.*

Vitamin K2 (MK-7) 100mcg

Vitamin K2 plays an important role in calcium utilization and normal arterial function, helping the body direct calcium toward bone where it belongs. onlyone™ Heart includes MK-7, the most bioavailable form, to complement vitamin D3 and support proper calcium balance.* If you take warfarin or another blood thinner, consult your doctor before use.

Nothing hidden. Everything labeled.

onlyone™ Heart is manufactured to the highest standards to ensure purity, safety, and effectiveness.
Highest Bioavailable Forms

Bioavailable forms of key nutrients help bypass any slow down with your body's conversion processes, getting you what you need faster: ubiquinol, methylcobalamin, magnesium glycinate. The forms research supports, not the cheapest available.

Third-Party Tested

Third-party tested for purity and potency.

Manufactured in the USA

Manufactured in an FDA-registered, GMP-certified facility in the USA.

No Unnecessary Additives

No artificial fillers. No unnecessary additives. No compromises on what goes in the capsule.

Pro-Doctor. Pro-You.

onlyone™ Heart was built to complement your prescribed therapy, not compete with it.

 

"There's a real difference between a kitchen-sink supplement and one built around evidence. The nutrients in this formula are the ones I find myself discussing most often with cardiac patients, delivered in forms the body can actually absorb and use."

 

— Julia Zumpano, Registered Dietician and member of the onlyone™ Heart Scientific Advisory Board

This is how simple it should be.

Still have questions? We’ve got honest answers.

Onlyone™ Heart is designed to work alongside, not replace or interfere with, your statin therapy. That said, if you have specific concerns, always run it by your cardiologist first. We’re pro-doctor, not a substitute for one.

Also, always consult with your physician before starting any new supplement regimen, particularly if you are taking other prescription medications. If you are on a blood thinner such as Warfarin, please consult your doctor before taking onlyone™ Heart, particularly regarding the Vitamin K2 content. Our formulation features MK-7 not the typical K1 that has known interactions with coumadin/Warfarin, but it's worth making sure your doctor feels comfortable with you taking it.*

Ubiquinol is the active, reduced form of CoQ10. Research suggests it’s better absorbed*, particularly for people over 40 whose bodies become less efficient at converting ubiquinone to the usable form*. It costs more to use. We use it anyway.

Every person is different, onlyone™ Heart is a dietary supplement, not a drug, and we don’t make specific outcome promises. Most nutritional supplements take several weeks to build up in your system. They support normal body functions over time rather than delivering an immediate effect. We recommend giving it at least 60 -90 days, which is why we offer a 60-day satisfaction guarantee.

Methylation is one of your body's most important behind-the-scenes processes — a constant chemical hand-off that happens billions of times a second, helping your body do everything from building DNA to processing certain compounds and keeping key systems running smoothly. B vitamins (B6, B9/folate, and B12) are essential helpers in this process.

Homocysteine is an amino acid your body produces normally as a byproduct of metabolizing methionine (an amino acid from protein in your diet). It's not meant to accumulate; your body continuously clears it through two pathways, and methylation is the main one.

Adequate active B vitamins keep the methylation pathway running, which is how the body maintains homocysteine in its normal range.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Always consult with your physician before starting any new supplement regimen, particularly if you are taking prescription medications. If you are on a blood thinner such as Warfarin, please consult your doctor before taking onlyone™ Heart.

See what our customers say

  • 5 stars: 6 (75%)
  • 4 stars: 2 (25%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
J
Jane

I am not a good sleeper, since starting only one Heart, I am sleeping much better. In general my energy level has definitely improved. I’m very happy to be adding this to my regular schedule.

J
Jim G.

I have been on statins for over 20 years plus lots of other piils and supplements. only one Heart has definitely made my mornnig pill routine simpler and easier and i already feel more energetic!

R
Ron B.

Am I crazy or what? I have only been taking Only One Heart capsules for two weeks and already I am feeling results! I am sleeping much more soundly and waking feeling refreshed and not that old “still tired” sensation. I am 81 years old and in the past needed an hour or two nap mid day. I don’t feel I need that now. I have much more energy all day. I can’t wait to see my results after a full month and beyond!

J
Jorge F.

I've been on a statin for years and wanted to support my heart better. This gives me the confidence that I'm doing the right thing everyday.

D
Dan L.

Excellent product. Great energy throughout the day when taken in morning. Look forward to taking this daily

W
William T.

Excellent product but amount per serving for vit D3, coQ10 and vitamin k2 should be higher.

S
Suzannah S.

So grateful to have onlyone Heart post so many heart diagnoses and info to help on the road to recovery.

L
Linda M.

Just received recently and finishing previous medicines already set up but looking forward to starting it soon as it replaces severel supplements we are already taking